| Assay ID | Title | Year | Journal | Article |
|---|
| AID1508630 | Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident proteome: Secreted ER Calcium Modulated Protein (SERCaMP) assay | 2021 | Cell reports, 04-27, Volume: 35, Issue:4
| A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. |
| AID1347154 | Primary screen GU AMC qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1656901 | Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 expression after 24 hrs by ethoxyresorufin-O-deethylase assay | 2020 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 30, Issue:5
| Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. |
| AID1656896 | Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 activity at 0.13 nM using 7-ethoxyresorufin as substrate after 24 hrs by ethoxyresorufin-O-deethylase assay relative to DMSO | 2020 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 30, Issue:5
| Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. |
| AID1706080 | Agonist activity at AhR in human HepG2 cells co-transfected with pSELECT-zeo-Lucia and CYP1A1 assessed as induction of receptor transactivation at 18 uM incubated for 24 hrs by luciferase reporter gene assay relative to control | 2020 | European journal of medicinal chemistry, Dec-01, Volume: 207 | Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes. |
| AID1656897 | Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 activity at 3.2 nM using 7-ethoxyresorufin as substrate after 24 hrs by ethoxyresorufin-O-deethylase assay relative to DMSO | 2020 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 30, Issue:5
| Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. |
| AID1656898 | Agonist activity at AhR in human HepG2 cells assessed as induction of CYP1A1 activity at 80 nM using 7-ethoxyresorufin as substrate after 24 hrs by ethoxyresorufin-O-deethylase assay relative to DMSO | 2020 | Bioorganic & medicinal chemistry letters, 03-01, Volume: 30, Issue:5
| Synthesis and biological evaluation of FICZ analogues as agonists of aryl hydrocarbon receptor. |
| AID1726760 | Activation of AhR in human HT29-Lucia cells expressing secreted Lucia luciferase reporter gene assessed as increase in receptor transactivation by measuring fold increase in reporter activity at 5 uM measured after 24 hrs by luciferase reporter gene assay | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6
| Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents. |
| AID1706087 | Agonist activity at AhR in human HepG2 cells assessed as induction of AhR transcriptional activity incubated for 24 hrs by Quanti-Luc reagent based luminescence assay | 2020 | European journal of medicinal chemistry, Dec-01, Volume: 207 | Targeting the aryl hydrocarbon receptor with a novel set of triarylmethanes. |
| AID1897748 | Downregulation of purmorphamine-induced Ptch2 mRNA expression in mouse C3H 10T1/2 cells at 1 uM measured after 48 hrs by RT-qPCR analysis | 2022 | Journal of medicinal chemistry, 12-22, Volume: 65, Issue:24
| The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. |
| AID1897744 | Inhibition of Hedgehog-signalling dependent purmorphamine induced osteoblast differentiation in mouse C3H 10T1/2 cells assessed as reduction in ALP expression at 0.01 to 100 uM incubated for 96 hrs by CDP-Star luminogenic substrate based assay | 2022 | Journal of medicinal chemistry, 12-22, Volume: 65, Issue:24
| The Highly Potent AhR Agonist Picoberin Modulates Hh-Dependent Osteoblast Differentiation. |
| AID393143 | Activation of AhR expressed in guinea pig cytosolic fractions over expressed with XRE by ELISA based Ah-immunoassay relative to TCDD | 2009 | Bioorganic & medicinal chemistry, Feb-15, Volume: 17, Issue:4
| Synthesis and biological evaluation of fused thio- and selenopyrans as new indolocarbazole analogues with aryl hydrocarbon receptor affinity. |
| AID1726750 | Activation of AhR in human HT29-Lucia cells expressing secreted Lucia luciferase reporter gene assessed as increase in receptor transactivation by measuring fold increase in reporter activity at 5 uM measured after 48 hrs by luciferase reporter gene assay | 2021 | RSC medicinal chemistry, Jun-23, Volume: 12, Issue:6
| Amino alcohol acrylonitriles as broad spectrum and tumour selective cytotoxic agents. |
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3
| High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |